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Itga3 Mouse shRNA Plasmid (Locus ID 16400)

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TG512258
Itga3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 16400
Synonyms AA407068; CD49C; GAPB3
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Itga3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 16400). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC053031, BC062205, NM_013565, NM_013565.1, NM_013565.2, NM_013565.3, BC023259, BC096741
UniProt ID Q62470
Summary This gene encodes a subunit of integrin family of cell surface proteins. The encoded protein undergoes post-translational processing to form a disulfide bond-linked dimer comprised of heavy and light chains. At the cell surface, the encoded protein non-covalently associates with the integrin beta-1 subunit to form a heterodimer that interacts with many extracellular matrix proteins including fibronectin and laminin. Mice lacking the encoded protein die during the first day after birth due to severe abnormalities in kidneys. Mice lacking the encoded protein specifically in the basal layer of epidermis display several skin defects and accelerated wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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