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Cyp2c44 Mouse shRNA Plasmid (Locus ID 226143)

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TG506724
Cyp2c44 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 226143
Synonyms AW107714; b2b386Clo; BC034834; Cyp2c44
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Cyp2c44 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 226143). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC025819, BC026766, BC034834, NM_001001446, NM_001167905, NM_001001446.1, NM_001001446.2, NM_001001446.3, NM_001167905.1, BC022141, BC024068
UniProt ID A0A1D5RLI1
Summary A cytochrome P450 monooxygenase involved in polyunsaturated fatty acids (PUFAs) metabolism and signaling (PubMed:15084647). Catalyzes preferentially the epoxidation of double bonds of PUFAs (PubMed:15084647). Converts arachidonoic acid primarily to stereospecific products (8R,9S)-epoxyeicosatrienoate (EET) and (11R,12S)-EET (PubMed:15084647). Via EETs may inhibit the epithelial sodium channels in nephron segments, leading to increased sodium excretion and stable systemic blood pressure (PubMed:24966089, PubMed:24368771). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:15084647).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.