Map1lc3b Mouse shRNA Plasmid (Locus ID 67443)

SKU
TG503902
Map1lc3b - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 67443
Synonyms 1010001C15Rik; Atg8; LC3b; Map1lc3
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Map1lc3b - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 67443). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC068180, BC110308, NM_026160, NM_026160.1, NM_026160.2, NM_026160.3, BC028812, BC086774, NM_001364358, NM_026160.5
UniProt ID Q9CQV6
Summary Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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