Keap1 Mouse shRNA Plasmid (Locus ID 50868)
SKU
TG502839
Keap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 50868 |
|---|---|
| Synonyms | INRF2; mKIAA0132 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | Keap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 50868). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC055732, NM_001110305, NM_001110306, NM_001110307, NM_016679, NM_001110307.1, NM_016679.1, NM_016679.2, NM_016679.3, NM_016679.4, NM_001110305.1, NM_001110306.1, BC006729, BC023945 |
| UniProt ID | Q9Z2X8 |
| Summary | Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.