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PAK1 Human shRNA Plasmid Kit (Locus ID 5058)

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TG320442
PAK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
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  $883.00
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Specifications
Specifications
Product Data
Locus ID 5058
Synonyms alpha-PAK; IDDMSSD; p65-PAK; PAKalpha
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PAK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5058). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001128620, NM_002576, NM_002576.1, NM_002576.2, NM_002576.3, NM_002576.4, NM_001128620.1, BC050377, BC109298, BC109299, BM451179, NM_001128620.2
UniProt ID Q13153
Summary This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Mutations in this gene have been associated with macrocephaly, seizures, and speech delay. Overexpression of this gene is also reported in many cancer types, and particularly in breast cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2020
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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