EMA (MUC1) Human shRNA Plasmid Kit (Locus ID 4582)

SKU
TG316625
MUC1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 4582
Synonyms ADMCKD; ADMCKD1; ADTKD2; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components MUC1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 4582). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001018016, NM_001018017, NM_001018021, NM_001044390, NM_001044391, NM_001044392, NM_001044393, NM_001204285, NM_001204286, NM_001204287, NM_001204288, NM_001204289, NM_001204290, NM_001204291, NM_001204292, NM_001204293, NM_001204294, NM_001204295, NM_001204296, NM_001204297, NM_002456, NM_182741, NM_001018017.1, NM_001018017.2, NM_002456.1, NM_002456.2, NM_002456.3, NM_002456.4, NM_002456.5, NM_001018016.1, NM_001018016.2, NM_001044392.1, NM_001044392.2, NM_001044390.1, NM_001044390.2, NM_001044391.1, NM_001044391.2, NM_001044393.1, NM_001044393.2, NM_001204297.1, NM_001204293.1, NM_001204295.1, NM_001204296.1, NM_001204290.1, NM_001204288.1, NM_001204294.1, NM_001204289.1, NM_001204292.1, NM_001204291.1, NM_001204287.1, NM_001204285.1, NM_001204286.1, BC120974, BC120975, BM969296, BM971650, NM_001044393.3, NM_001204296.2, NM_001204297.2, NM_001018016.3, NM_001204294.2, NM_001044390.3, NM_001204285.2, NM_001204287.2, NM_001204289.2, NM_001044391.3, NM_001204290.2, NM_001204293.2, NM_001044392.3, NM_001204288.2, NM_002456.6, NM_001018017.3
UniProt ID P15941
Summary This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.provided by RefSeq, Feb 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.