G protein coupled receptor 30 (GPER1) Human shRNA Plasmid Kit (Locus ID 2852)

SKU
TG316565
GPER1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 2852
Synonyms FEG-1, LERGU, CMKRL2, LERGU2, GPCR-Br, MGC99678
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components GPER1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 2852). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001031682, NM_001039966, NM_001098201, NM_001505, NM_001039966.1, NM_001098201.1, NM_001505.1, NM_001505.2, BC011634, BC011634.1, BC067849, BC082766, BM672716, NM_001505.3, NM_001098201.3
UniProt ID Q99527
Summary This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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