Alkaline Phosphatase (ALPL) Human shRNA Plasmid Kit (Locus ID 249)

SKU
TG314817
ALPL - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 249
Synonyms AP-TNAP; APTNAP; HOPS; HPPA; HPPC; HPPI; HPPO; TNALP; TNAP; TNSALP
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components ALPL - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 249). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_000478, NM_001127501, NM_001177520, NM_000478.1, NM_000478.2, NM_000478.3, NM_000478.4, NM_000478.5, NM_001127501.1, NM_001127501.2, NM_001127501.3, NM_001177520.1, NM_001177520.2, BC021289, BC021289.2, BC066116, BC090861, BC110909, BC126165, BC136325, NM_001369805, NM_001369803, NM_001369804
UniProt ID P05186
Summary This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. provided by RefSeq, Oct 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.