Ankyrin G (ANK3) Human shRNA Plasmid Kit (Locus ID 288)

SKU
TG314794
ANK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 288
Synonyms ANKYRIN-G; MRT37
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components ANK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 288). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001149, NM_001204403, NM_001204404, NM_020987, NM_001320874, NM_001149.1, NM_001149.2, NM_001149.3, NM_020987.1, NM_020987.2, NM_020987.3, NM_020987.4, NM_001204403.1, NM_001204404.1, NM_020987.5, NM_001204403.2, NM_001204404.2
UniProt ID Q12955
Summary Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Feb 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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