Bak (BAK1) Human shRNA Plasmid Kit (Locus ID 578)

SKU
TG314515
BAK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 578
Synonyms BAK; BAK-LIKE; BCL2L7; CDN1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components BAK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 578). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001188, NM_001188.1, NM_001188.2, NM_001188.3, BC004431, BC004431.1, BC032789, BC110337, BM855203, NM_001188.4
UniProt ID Q16611
Summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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