Nicotinic Acetylcholine Receptor alpha 4 (CHRNA4) Human shRNA Plasmid Kit (Locus ID 1137)
SKU
TG313920
CHRNA4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1137 |
|---|---|
| Synonyms | BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | CHRNA4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1137). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_000744, NM_001256573, NR_046317, NM_000744.1, NM_000744.2, NM_000744.3, NM_000744.4, NM_000744.5, NM_000744.6, NM_001256573.1, BC096290, BC096291, BC096292, BC096293, BM710937, NM_001256573.2 |
| UniProt ID | P43681 |
| Summary | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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in shipping.