CYP24A1 Human shRNA Plasmid Kit (Locus ID 1591)

SKU
TG313603
CYP24A1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 1591
Synonyms CP24; CYP24; HCAI; HCINF1; P450-CC24
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components CYP24A1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1591). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_000782, NM_001128915, NM_000782.1, NM_000782.2, NM_000782.3, NM_000782.4, NM_001128915.1, BC109083, BC109084, BM928702, NM_001128915.2, NM_000782.5
UniProt ID Q07973
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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