ELAVL1 Human shRNA Plasmid Kit (Locus ID 1994)

SKU
TG313235
ELAVL1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 1994
Synonyms ELAV1; Hua; HUR; MelG
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components ELAVL1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1994). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001419, NM_001419.1, NM_001419.2, BC003376, BC003376.2, BM664469, BM696191, NM_001419.3
UniProt ID Q15717
Summary The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. provided by RefSeq, Sep 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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