EVI1 (MECOM) Human shRNA Plasmid Kit (Locus ID 2122)

SKU
TG313148
MECOM - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 2122
Synonyms AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components MECOM - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 2122). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001105077, NM_001105078, NM_001163999, NM_001164000, NM_001205194, NM_004991, NM_005241, NM_005241.1, NM_005241.2, NM_001105078.1, NM_001105078.2, NM_001105078.3, NM_001105077.1, NM_001105077.2, NM_001105077.3, NM_001164000.1, NM_001163999.1, NM_004991.3, NM_001205194.1, BC069498, BC143952, BC130520, BC012450, BC031019, BC143951, NM_001366467, NM_001366469, NM_001366470, NM_001366471, NM_001366466, NM_001366468, NM_001366472, NM_001366473, NM_001366474, NM_001205194.2, NM_001164000.2, NM_001105078.4, NM_004991.4, NM_005241.4
UniProt ID Q13465
Summary The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. provided by RefSeq, Mar 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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