PBX1 Human shRNA Plasmid Kit (Locus ID 5087)
SKU
TG310592
PBX1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 5087 |
|---|---|
| Synonyms | CAKUHED |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | PBX1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5087). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001204961, NM_001204963, NM_002585, NM_001353130, NM_001353131, NM_002585.2, NM_002585.3, NM_001204961.1, NM_001204963.1, BC101578, BC101578.1, BC044624, BC143435, BC143451, NM_002585.4, NM_001204961.2 |
| UniProt ID | P40424 |
| Summary | This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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in shipping.