ALIX (PDCD6IP) Human shRNA Plasmid Kit (Locus ID 10015)
SKU
TG310557
PDCD6IP - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 10015 |
|---|---|
| Synonyms | AIP1; ALIX; DRIP4; HP95 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | PDCD6IP - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 10015). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001162429, NM_001256192, NM_013374, NR_027867, NR_027868, NM_013374.2, NM_013374.3, NM_013374.4, NM_013374.5, NM_001162429.1, NM_001162429.2, NM_001256192.1, BC020066, BC020066.1, BC068454, BM669193, NM_013374.6 |
| UniProt ID | Q8WUM4 |
| Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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