RGS5 Human shRNA Plasmid Kit (Locus ID 8490)

SKU TG309832

RGS5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 8490
• Synonyms: MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: RGS5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 8490). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_001195303, NM_001254748, NM_001254749, NM_003617, NR_045630, NM_003617.1, NM_003617.2, NM_003617.3, NM_001195303.1, NM_001195303.2, NM_001254748.1, NM_001254749.1, BC030059, BC030059.1, BC029357, BC032239, NM_001195303.3, NM_001254749.2, NM_003617.4
• UniProt ID: O15539
• Summary: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient