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SAP155 (SF3B1) Human shRNA Plasmid Kit (Locus ID 23451)

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TG309508
SF3B1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 23451
Synonyms Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components SF3B1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 23451). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001005526, NM_001308824, NM_012433, NM_001005526.1, NM_001005526.2, NM_012433.2, BC015530, BC029418, BC039020, BC046140, BC056155, BC064335, BC107883, NM_012433.4
UniProt ID O75533
Summary This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.