SMPDL3B Human shRNA Plasmid Kit (Locus ID 27293)

SKU
TG309229
SMPDL3B - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 27293
Synonyms ASML3B
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components SMPDL3B - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 27293). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001009568, NM_001304579, NM_014474, NM_001009568.1, NM_001009568.2, NM_014474.1, NM_014474.2, NM_014474.3, BC014444, BC014444.1, NM_014474.4
UniProt ID Q92485
Summary Lipid-modulating phosphodiesterase (PubMed:26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed:26095358). Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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