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SPINK5 Human shRNA Plasmid Kit (Locus ID 11005)

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TG309144
SPINK5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 11005
Synonyms LEKTI; LETKI; NETS; NS; VAKTI
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components SPINK5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 11005). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001127698, NM_001127699, NM_006846, NM_006846.1, NM_006846.2, NM_006846.3, NM_001127699.1, NM_001127698.1, BC141545, NM_006846.4, NM_001127698.2, NM_001127699.2
UniProt ID Q9NQ38
Summary This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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