VPS4B Human shRNA Plasmid Kit (Locus ID 9525)

SKU
TG308403
VPS4B - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
In Control Promo
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 9525
Synonyms MIG1; SKD1; SKD1B; VPS4-2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components VPS4B - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 9525). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_004869, NM_004869.1, NM_004869.2, NM_004869.3, BC039574, BC039574.1, BC009692, NM_004869.4
UniProt ID O75351
Summary The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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