beta Arrestin 1 (ARRB1) Human shRNA Plasmid Kit (Locus ID 408)

SKU
TG306568
ARRB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 408
Synonyms ARB1; ARR1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components ARRB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 408). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC003636, NM_004041, NM_020251, NM_004041.1, NM_004041.2, NM_004041.3, NM_004041.4, NM_020251.1, NM_020251.2, BC003636.2, BM681392, NM_004041.5, NM_020251.4
UniProt ID P49407
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. provided by RefSeq, Jan 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.