Cathepsin L (CTSL) Human shRNA Plasmid Kit (Locus ID 1514)
SKU
TG305172
CTSL1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1514 |
|---|---|
| Synonyms | CATL; CTSL1; MEP |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | CTSL1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1514). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001257971, NM_001257972, NM_001257973, NM_001912, NM_145918, NM_001912.1, NM_001912.2, NM_001912.3, NM_001912.4, NM_145918.1, NM_145918.2, NM_001257973.1, NM_001257971.1, NM_001257972.1, BC012612, BC012612.1, BC142983, BM680778, NM_001257973.2, NM_001257971.2, NM_001257972.2, NM_001912.5, NM_145918.3 |
| UniProt ID | P07711 |
| Summary | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. provided by RefSeq, Aug 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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