DHH Human shRNA Plasmid Kit (Locus ID 50846)

SKU
TG305011
DHH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 50846
Synonyms GDMN; GDXYM; HHG-3; SRXY7
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components DHH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 50846). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_021044, NM_021044.1, NM_021044.2, NM_021044.3, BC033507, BC033507.1, NM_021044.4
UniProt ID O43323
Summary This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. provided by RefSeq, May 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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