Lamin A (LMNA) Human shRNA Plasmid Kit (Locus ID 4000)
SKU
TG303510
LMNA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 4000 |
|---|---|
| Synonyms | CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; PRO1 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | LMNA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 4000). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001257374, NM_001282624, NM_001282625, NM_001282626, NM_005572, NM_170707, NM_170708, NR_047544, NR_047545, NM_005572.1, NM_005572.2, NM_005572.3, NM_170707.1, NM_170707.2, NM_170707.3, NM_170708.1, NM_170708.2, NM_001257374.1, NM_001257374.2, NM_001282624.1, NM_001282625.1, NM_001282626.1, BC000511, BC000511.2, BC014507, BC014507.1, BC003162, BC018863, BC033088, NM_001282626.2, NM_001282624.2, NM_001257374.3, NM_005572.4, NM_170707.4, NM_001282625.2, NM_170708.4 |
| UniProt ID | P02545 |
| Summary | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. provided by RefSeq, Apr 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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