LYRIC (MTDH) Human shRNA Plasmid Kit (Locus ID 92140)
SKU
TG303120
MTDH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 92140 |
|---|---|
| Synonyms | 3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MTDH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 92140). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_178812, NM_178812.1, NM_178812.2, NM_178812.3, BC045642, BC045642.1, BC001815, BC009324, BC014977, BC022825, BC023994, NM_001363139, NM_001363136, NM_001363137, NM_001363138 |
| UniProt ID | Q86UE4 |
| Summary | Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.