PCDHA4 Human shRNA Plasmid Kit (Locus ID 56144)

SKU
TG302634
PCDHA4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 56144
Synonyms CNR1; CNRN1; CRNR1; PCDH-ALPHA4
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components PCDHA4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 56144). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_018907, NM_031500, NM_031500.1, NM_031500.2, NM_018907.1, NM_018907.2, NM_018907.3, BC112102, BC112102.1, BC113609, NM_018907.4, NM_031500.3
UniProt ID Q9UN74
Summary This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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