PKM2 (PKM) Human shRNA Plasmid Kit (Locus ID 5315)

SKU
TG302462
PKM2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 5315
Synonyms CTHBP; HEL-S-30; OIP3; p58; PK3; PKM2; TCB; THBP1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components PKM2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5315). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001206796, NM_001206797, NM_001206798, NM_001206799, NM_001316318, NM_002654, NM_182470, NM_182471, NM_002654.1, NM_002654.2, NM_002654.3, NM_002654.4, NM_002654.5, NM_182470.1, NM_182470.2, NM_182470.3, NM_182471.1, NM_182471.2, NM_182471.3, NM_001206797.1, NM_001206797.2, NM_001206798.1, NM_001206798.2, NM_001206799.1, NM_001206796.1, NM_001206796.2, BC000481, BC000481.2, BC007640, BC007952, BC012811, BC019265, BC023328, BC023592, BC035198, BC035487, BC094767, BC096823, NM_001206796.3, NM_182471.4, NM_001206799.2, NM_002654.6
UniProt ID P14618
Summary This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. provided by RefSeq, May 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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