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RAD51 Human shRNA Plasmid Kit (Locus ID 5888)

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TG302130
RAD51 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 5888
Synonyms BRCC5; FANCR; HRAD51; HsRad51; HsT16930; MRMV2; RAD51A; RECA
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components RAD51 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5888). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001164269, NM_001164270, NM_002875, NM_133487, NM_133487.1, NM_133487.2, NM_133487.3, NM_002875.1, NM_002875.2, NM_002875.3, NM_002875.4, NM_001164270.1, NM_001164269.1, BC001459, BC001459.2, NM_001164270.2, NM_002875.5, NM_001164269.2
UniProt ID Q06609
Summary The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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