Dexras1 (RASD1) Human shRNA Plasmid Kit (Locus ID 51655)

SKU
TG302107
RASD1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 51655
Synonyms AGS1; DEXRAS1; MGC:26290
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components RASD1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 51655). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001199989, NM_016084, NM_016084.1, NM_016084.2, NM_016084.3, NM_016084.4, NM_001199989.1, BC018041, BC018041.1, BC042688, NM_016084.5, NM_001199989.2
UniProt ID Q9Y272
Summary This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Sep 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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