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SPATA13 Human shRNA Plasmid Kit (Locus ID 221178)

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SKU
TG301435
SPATA13 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 221178
Synonyms ARHGEF29; ASEF2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components SPATA13 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 221178). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001166271, NM_001286792, NM_001286793, NM_001286794, NM_001286795, NM_153023, NR_104595, NM_153023.1, NM_153023.2, NM_153023.3, NM_001166271.1, NM_001166271.2, NM_001286795.1, NM_001286794.1, NM_001286792.1, BC109290, BC043582, BC109291, NM_001286795.2, NM_001286792.2, NM_001166271.3, NM_001286793.2, NM_153023.4
UniProt ID Q96N96
Summary Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.