Cbs Mouse shRNA Plasmid (Locus ID 12411)

SKU
TF515298
Cbs - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 12411
Synonyms AI047524; AI303044; HIP4
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components Cbs - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 12411). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC013472, BC013480, BC026595, NM_001271353, NM_144855, NM_178224, NM_178224.1, NM_178224.2, NM_178224.3, NM_144855.1, NM_144855.2, NM_144855.3, NM_001271353.1, BC022144
UniProt ID Q91WT9
Summary Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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