Fas Mouse shRNA Plasmid (Locus ID 14102)

SKU
TF513574
Fas - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 14102
Synonyms AI196731; APO1; APT1; CD95; lpr; TNFR6; Tnfrsf6
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components Fas - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 14102). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC061160, NM_001146708, NM_007987, NM_007987.1, NM_007987.2, NM_001146708.1
UniProt ID P25446
Summary Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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