Pik3c3 Mouse shRNA Plasmid (Locus ID 225326)
Specifications
| Product Data | |
| Locus ID | 225326 |
|---|---|
| Synonyms | 5330434F23Rik; Vps34 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pik3c3 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 225326). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC024675, BC057678, NM_181414, NR_151699, NM_181414.1, NM_181414.2, NM_181414.3, NM_181414.4, NM_181414.5, BC027029, NM_181414.6 |
| UniProt ID | Q6PF93 |
| Summary | Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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