Ptprc Mouse shRNA Plasmid (Locus ID 19264)
Specifications
| Product Data | |
| Locus ID | 19264 |
|---|---|
| Synonyms | B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ptprc - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 19264). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001111316, NM_001268286, NM_011210, NM_001111316.1, NM_001111316.2, NM_011210.1, NM_011210.2, NM_011210.3, NM_011210.4, NM_001268286.1, BC028512, BC084684, BC131655, BC167212, BM239381 |
| UniProt ID | P06800 |
| Summary | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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