Gtf2i Mouse shRNA Plasmid (Locus ID 14886)
Specifications
| Product Data | |
| Locus ID | 14886 |
|---|---|
| Synonyms | 6030441I21Rik; BAP-135; Diws1t; GtfII-I; Spin; TFII-I; WBSCR6 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Gtf2i - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 14886). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC053044, NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, NM_001359062, NM_001359063, NM_001359064, NM_001359065, NM_001359066, NM_001359067, NM_001080746.1, NM_001080746.2, NM_010365.1, NM_010365.2, NM_010365.3, NM_010365.4, NM_001080747.1, NM_001080747.2, NM_001080748.1, NM_001080748.2, NM_001080749.1, NM_001080749.2, BC047387 |
| UniProt ID | Q9ESZ8 |
| Summary | Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box (By similarity). Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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