Gfra1 Mouse shRNA Plasmid (Locus ID 14585)
Specifications
| Product Data | |
| Locus ID | 14585 |
|---|---|
| Synonyms | AU042498; GDNFR; GFRalpha-1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Gfra1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 14585). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC054378, NM_001285457, NM_010279, NR_104342, NM_010279.1, NM_010279.2, NM_010279.3, NM_001285457.1, NM_001285457.2, BC011532, BC040251, BC044783 |
| UniProt ID | P97785 |
| Summary | This gene encodes a transmembrane protein that functions as the receptor for glial cell line derived neurotrophic factor (GDNF). The encoded protein undergoes proteolytic processing to generate a glycosylphosphatidylinositol-anchored cell surface coreceptor that forms a complex with the Ret tyrosine kinase in GDNF signaling pathway. Mice lacking the encoded protein exhibit deficits in the kidneys, the enteric nervous system, and spinal motor and sensory neurons similar mice deficient in GDNF or Ret. provided by RefSeq, Jul 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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