Dnmt3b Mouse shRNA Plasmid (Locus ID 13436)

SKU
TF500550
Dnmt3b - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 13436
Synonyms MmuIIIB
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Dnmt3b - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 13436). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC105677, BC105922, NM_001003960, NM_001003961, NM_001003963, NM_001122997, NM_001271744, NM_001271745, NM_001271746, NM_001271747, NM_010068, NM_001003961.1, NM_001003961.2, NM_001003961.3, NM_001003961.4, NM_001003960.1, NM_001003960.2, NM_001003960.3, NM_001003960.4, NM_010068.1, NM_010068.2, NM_010068.3, NM_010068.4, NM_010068.5, NM_001003963.1, NM_001003963.2, NM_001003963.3, NM_001003963.4, NM_001122997.1, NM_001122997.2, NM_001271747.1, NM_001271746.1, NM_001271745.1, NM_001271744.1
UniProt ID O88509
Summary This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. provided by RefSeq, Nov 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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