Dnmt3b Mouse shRNA Plasmid (Locus ID 13436)
Specifications
| Product Data | |
| Locus ID | 13436 |
|---|---|
| Synonyms | MmuIIIB |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dnmt3b - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 13436). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC105677, BC105922, NM_001003960, NM_001003961, NM_001003963, NM_001122997, NM_001271744, NM_001271745, NM_001271746, NM_001271747, NM_010068, NM_001003961.1, NM_001003961.2, NM_001003961.3, NM_001003961.4, NM_001003960.1, NM_001003960.2, NM_001003960.3, NM_001003960.4, NM_010068.1, NM_010068.2, NM_010068.3, NM_010068.4, NM_010068.5, NM_001003963.1, NM_001003963.2, NM_001003963.3, NM_001003963.4, NM_001122997.1, NM_001122997.2, NM_001271747.1, NM_001271746.1, NM_001271745.1, NM_001271744.1 |
| UniProt ID | O88509 |
| Summary | This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. provided by RefSeq, Nov 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.