IRAK4 Human shRNA Plasmid Kit (Locus ID 51135)
Specifications
| Product Data | |
| Locus ID | 51135 |
|---|---|
| Synonyms | IMD67; IPD1; IRAK-4; NY-REN-64; REN64 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | IRAK4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 51135). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001114182, NM_001145256, NM_001145257, NM_001145258, NM_016123, NM_001351338, NM_001351339, NM_001351340, NM_001351341, NM_001351342, NM_001351343, NM_001351344, NM_001351345, NM_016123.1, NM_016123.2, NM_016123.3, NM_001114182.1, NM_001114182.2, NM_001145256.1, NM_001145257.1, NM_001145258.1, BC013316, BC013316.1, NM_016123.4 |
| UniProt ID | Q9NWZ3 |
| Summary | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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