SIK3 Human shRNA Plasmid Kit (Locus ID 23387)
SKU
TF320669
SIK3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 23387 |
|---|---|
| Synonyms | L19; QSK; SEMDK; SIK-3 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | SIK3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 23387). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001281748, NM_001281749, NM_025164, NM_025164.1, NM_025164.2, NM_025164.3, NM_025164.4, NM_001281748.1, NM_001281749.1, BC035583, BC063887, BC086858, BC121188, BC128510, BC128511, BM127054, BM682365, NM_001366686, NM_001366687, NM_001281749.3, NM_001281748.3 |
| UniProt ID | Q9Y2K2 |
| Summary | Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis (PubMed:30232230). Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.