BRD2 Human shRNA Plasmid Kit (Locus ID 6046)
Specifications
| Product Data | |
| Locus ID | 6046 |
|---|---|
| Synonyms | BRD2-IT1; D6S113E; FSH; FSRG1; NAT; O27.1.1; RING3; RNF3 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BRD2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 6046). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001113182, NM_001199455, NM_001199456, NM_001291986, NM_005104, NR_037625, NM_005104.1, NM_005104.2, NM_005104.3, NM_001113182.1, NM_001113182.2, NM_001199456.1, NM_001199455.1, NM_001291986.1, BC000477, BC001885, BC007715, BC063840, NM_001291986.2, NM_001113182.3 |
| UniProt ID | P25440 |
| Summary | This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. provided by RefSeq, Dec 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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