ROR1 Human shRNA Plasmid Kit (Locus ID 4919)
Specifications
| Product Data | |
| Locus ID | 4919 |
|---|---|
| Synonyms | dJ537F10.1; NTRKR1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ROR1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 4919). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001083592, NM_005012, NM_005012.1, NM_005012.2, NM_005012.3, NM_001083592.1, BC006374, BC080541, BC128386, BC156511, BC172555, NM_005012.4 |
| UniProt ID | Q01973 |
| Summary | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jun 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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