TrkA (NTRK1) Human shRNA Plasmid Kit (Locus ID 4914)

SKU
TF320435
NTRK1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 4914
Synonyms MTC, TRK, TRK1, TRKA, p140-TrkA
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components NTRK1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 4914). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001007204, NM_001007792, NM_001012331, NM_002529, NM_002529.1, NM_002529.2, NM_002529.3, NM_001012331.1, NM_001007792.1, BC062580, BC136554, BC144239, BM685020
UniProt ID P04629
Summary This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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