LCK Human shRNA Plasmid Kit (Locus ID 3932)
Specifications
| Product Data | |
| Locus ID | 3932 |
|---|---|
| Synonyms | IMD22; LSK; p56lck; pp58lck; YT16 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LCK - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 3932). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001042771, NM_001330468, NM_005356, NM_005356.1, NM_005356.2, NM_005356.3, NM_005356.4, NM_001042771.1, NM_001042771.2, BC013200, NM_005356.5 |
| UniProt ID | P06239 |
| Summary | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. provided by RefSeq, Aug 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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