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IGF1 Receptor (IGF1R) Human shRNA Plasmid Kit (Locus ID 3480)

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SKU
TF320384
IGF1R - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 3480
Synonyms CD221; IGFIR; IGFR; JTK13
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components IGF1R - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 3480). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_000875, NM_001291858, NM_000875.2, NM_000875.3, NM_000875.4, NM_001291858.1, BC113610, BC010607, BC078157, BC088377, BC107089, BC111046, BC113612, BC143721, BM264223, NM_001291858.2, NM_000875.5
UniProt ID P08069
Summary This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, May 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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