HNF 4 alpha (HNF4A) Human shRNA Plasmid Kit (Locus ID 3172)
Specifications
| Product Data | |
| Locus ID | 3172 |
|---|---|
| Synonyms | FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | HNF4A - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 3172). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_000457, NM_001030003, NM_001030004, NM_001258355, NM_001287182, NM_001287183, NM_001287184, NM_175914, NM_178849, NM_178850, NM_001030003.1, NM_001030003.2, NM_178849.1, NM_178849.2, NM_175914.3, NM_175914.4, NM_001030004.1, NM_001030004.2, NM_000457.1, NM_000457.2, NM_000457.3, NM_000457.4, NM_178850.1, NM_178850.2, NM_001258355.1, NM_001287184.1, NM_001287182.1, NM_001287183.1, BC137539, BC137540, NM_000457.5, NM_178850.3, NM_001030003.3, NM_001287182.2, NM_178849.3, NM_001287184.2, NM_001258355.2, NM_001030004.3, NM_000457.6 |
| UniProt ID | P41235 |
| Summary | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. provided by RefSeq, Apr 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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