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VEGF Receptor 1 (FLT1) Human shRNA Plasmid Kit (Locus ID 2321)

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TF320360
FLT1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 2321
Synonyms FLT; FLT-1; VEGFR-1; VEGFR1
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components FLT1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 2321). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001159920, NM_001160030, NM_001160031, NM_002019, NM_002019.1, NM_002019.2, NM_002019.3, NM_002019.4, NM_001160031.1, NM_001160030.1, NM_001159920.1, BC039007, BC029849, NM_001159920.2, NM_001160030.2
UniProt ID P17948
Summary This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.provided by RefSeq, May 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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