FGFR1 Human shRNA Plasmid Kit (Locus ID 2260)
SKU
TF320354
FGFR1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 2260 |
|---|---|
| Synonyms | H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, CD331, N-SAM |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | FGFR1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 2260). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_000604, NM_001174063, NM_001174064, NM_001174065, NM_001174066, NM_001174067, NM_015850, NM_023105, NM_023106, NM_023107, NM_023108, NM_023109, NM_023110, NM_023111, NM_032191, NM_001354367, NM_001354368, NM_001354369, NM_001354370, NM_023110.1, NM_023110.2, NM_023105.1, NM_023105.2, NM_023107.1, NM_023107.2, NM_023108.1, NM_023108.2, NM_015850.2, NM_015850.3, NM_023106.1, NM_023106.2, NM_001174066.1, NM_001174064.1, NM_001174065.1, NM_001174063.1, NM_001174067.1, NM_023111.1, BC018128, BC018128.1, BC091494, BC015035, NM_023110.3, NM_001174064.2, NM_023105.3, NM_023106.3, NM_001174066.2, NM_001174063.2, NM_001174065.2, NM_015850.4 |
| UniProt ID | P11362 |
| Summary | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.