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CDC2L2 Human shRNA Plasmid Kit (Locus ID 985)

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SKU
TF320290
CDC2L2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 985
Synonyms CDC2L3, p58GTA, PITSLRE, CDK11-p46, CDK11-p58, MGC131975, CDK11-p110
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CDC2L2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 985). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_033527, NM_033528, NM_033531, NM_033532, NM_033534, NM_033536, NM_033537, NM_033621, NM_033532.1, NM_033529.1, NM_024011.1, NM_033527.1, NM_033528.1, NM_033531.1, NM_033534.1, NM_033536.1, NM_033537.1, NM_033621.1
Summary This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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