MCK10 (DDR1) Human shRNA Plasmid Kit (Locus ID 780)
Specifications
| Product Data | |
| Locus ID | 780 |
|---|---|
| Synonyms | CAK; CD167; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DDR1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 780). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001202521, NM_001202522, NM_001202523, NM_001297652, NM_001297653, NM_001297654, NM_001954, NM_013993, NM_013994, NM_001954.1, NM_001954.2, NM_001954.3, NM_001954.4, NM_013993.1, NM_013993.2, NM_013994.1, NM_013994.2, NM_001202521.1, NM_001202522.1, NM_001202523.1, NM_001297652.1, NM_001297653.1, NM_001297654.1, BC013400, BC013400.2, BC008716, BC070070, BM875592 |
| UniProt ID | Q08345 |
| Summary | Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Feb 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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